4.19.2009

AIDS treatment

For AIDS, there is no cause of treatment effects. The general principle of anti-infective therapy, anti-tumor, to kill or suppress HIV virus, enhance immune function.

Anti-infection treatment for various opportunistic infections and co-infection agents:

a, anti-virus-type infection drugs: herpes virus infection acyclovir can be used, each 800 mg oral 4 times a day, sharing two weeks, adverse reactions are skin rash, liver and kidney damage and reduced the reserve cells, but showed less that can be tolerated. Choice of cytomegalovirus infection-doped phosphate salts, C 1 Guanosine oxygen, can also choose Vidarabine. For broad-spectrum antiviral ribavirin on HIV RNA and DNA are effective, each 200 mg per 8-hour intravenous infusion once a small adverse reactions, patients can be tolerated.

##CONTINUE##b, anti-bacterial infections in medicine: try to choose efficient needle end of antibiotic use to infection control. Mycobacterium-infected persons to the use of rifampicin, 600 mg oral daily; of staphylococcal infection combined with triethylamine kanamycin enhanced efficacy. And streptococcal infection, and they should be taken into account for the multi-resistant strains, should be selected β-lactamases resistant to drugs such as minocycline, erythromycin azithromycin, roxithromycin and so on; for non-typhoid Salmonella, enteric bacilli infection, gram-negative bacteria should be selected on the effective or broad-spectrum antibiotics, such as cephalosporin or quinolone drug adriamycin.

c, anti-fungal drugs: the shallow part of the fungal infection than the limitations of the available topical cream, can be generalized from oral ketoconazole; of Candida dermatitis or oral, vaginal inflammation, ADM system can be used with the tablet and suppository local applications of rare strains, and poor response to ketoconazole and fluconazole, and the use of amphotericin B therapy.

d, antibiotics antigen Insects: Pneumocystis carinii pneumonia choose cotrimoxazole, dapsone and pentane sulfonic acid hydroxyethyl microphone. TMP currently considered as the preferred drug for each dose of 3 ~ 4, 3 times a day. As a result of high-dose applications, can cause neutropenia and hepatitis. Such as cotrimoxazole application null and void after 1 week should be to switch to other drugs. Of critically ill patients may increase corticosteroid used to improve the success rate. General selection of toxoplasmosis pyrimethamine, 25 to 100 mg per day, doubling the volume of the first. With sulfadiazine and sulfamethyldiazine Sulfadimidine combination can enhance the effectiveness of treatment. Clindamycin can be selected, particularly for choroidal significant effect of infection.

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